What's so insulting about Lost?

One day the CAD guy published Lost and the internet collectively lost its shit on how it's insulting. At the time I didn't know the internet lost its shit, saw it, and moved on with my life. Today it found its way to my twitter feed and about 75% of the comments were "hurhurhur it's lost and therefore a meme" but there were still some women were still insulted by it after all these years. Why?

Edit: loss, not lost. They cropped the name.